Cancer research is a field based solely upon the eradication of the lethal disease that has plagued humanity. Scientists have to discover techniques to manage cancerous gene changes. Those mutated messages can cause cells to evade normal growth controls and become cancer.
Some recent movements in the world of cancer research include:
Immunotherapy-
checkpoint inhibitors
monoclonal antibodies
adoptive cell transfer
immune system modulator
cancer vaccinnes
Gene based treatments -
Diagnose the cancer
Predict your outcome
Determine which drug or other treatment will work best on the cancer
See how well the treatment is working
Currently, the more effective between the two could argueably be immunotherapy. It is also called biological therapy. It is defined as a cancer treatment that raises cancer immunity utilizing substances made in vitro.
Immunotherapy works by:
Stopping or slowing the growth of cancer cells
Stopping cancer from spreading to other parts of the body
Helping the immune system work better at destroying cancer cells
Recent cancer research abstract-
"Lymphocyte-activation gene 3 (LAG-3) is an immune inhibitory receptor, with major histocompatibility complex class II (MHC-II) as a canonical ligand. However, it remains controversial whether MHC-II is solely responsible for the inhibitory function of LAG-3. Here, we demonstrate that fibrinogen-like protein 1 (FGL1), a liver-secreted protein, is a major LAG-3 functional ligand independent from MHC-II. FGL1 inhibits antigen-specific T cell activation, and ablation of FGL1 in mice promotes T cell immunity. Blockade of the FGL1-LAG-3 interaction by monoclonal antibodies stimulates tumor immunity and is therapeutic against established mouse tumors in a receptor-ligand inter-dependent manner. FGL1 is highly produced by human cancer cells, and elevated FGL1 in the plasma of cancer patients is associated with a poor prognosis and resistance to anti-PD-1/B7-H1 therapy. Our findings reveal an immune evasion mechanism and have implications for the design of cancer immunotherapy."(https://www.ncbi.nlm.nih.gov/pubmed/30580966/)
These findings could be an effective template for another successful basis of cancer combative immunotheraphy.
Cancer Research scientists are studying new treatments based on gene changes in cancer cells. These studies could lead to even more targeted immunotherapies and gene therapies in the future.
