Showing posts with label fruit. Show all posts
Showing posts with label fruit. Show all posts

Friday, September 28, 2018

Pumpkins and Beta-carotene

     Pumpkin is a tasty fruit.  It's a fruit because it has seeds.  Pumpkins are orange.  When made to be an ingredient, the food will be tinted orange.  There are numerous ways to partake of the delicious gourd. Choose one, and enjoy it for all of the benefits it gives.

     Pumpkins and pumpkins' seeds simultaneously supplement healthy diets.  Pumpkin pulp is a superb source of Beta-carotene. 

     Beta-Carotene Molecular Formula: C40H56

     Carotenoids are red, orange, and yellow pigments.  Beta-carotene is a carotenoid.  Incidentally, Beta-carotene is a precursor of vitamin A. Beta-carotene is derived from fruits, vegetables, and whole grains.

     Biosynthesis of carotenoids-

     The pathway begins with three molecules of acetyl CoA.  Those three acetyl CoA molecules plus mevalonic acid, synthesize isopentanyl pyrophosphate(IPP).  In the succeeding step of the pathway, geranylgeranyl pyrophosphate(GGPP) is produced by the condensation of dimethyl allyl pyrophosphate(DMAPP) with a molecule of isopentanyl pyrophosphate(IPP).  It is followed by the addition of two IPP units using GGPP synthase.  A two molecule reaction between  GGPP yields phytoene. The phytoene enzyme is faithful in the biosynthesis of the carotenoid biosynthetic pathway. The first C40 hydrocarbon, an important intermediate of phytoene, undergoes a series of desaturation reactions resulting in the formation of zeta-carotene(2-carotene) and lycopene.  Four desaturase reactions are catalysed by two related enzymes: phytoene desaturase(PDS) and 2-zeta-carotene desaturases (ZDS). The enzyme introduces double bonds in the phytoene. Lycopene has a pink color. The products yield carotene with two types of rings, B and E rings.  B rings yield beta- carotene, and E rings yield alpha-carotene.  The pathway branches at this point. The enzyme lycopene-beta-cyclases are responsible for cyclization of lycopene.  Two beta-rings are introduced at the ends of the linear lycopene molecule. 

     Beta-carotene uses:

     Decreases (exercise-induced) asthma.  It also prevents certain cancers, age related macular degeneration(AMD), treats AIDS,  alcoholism, Alzheimer's, alcoholism, disease, depression, epilepsy,  headache, heartburn, high blood pressure, infertility, Parkinson’s disease, rheumatoid arthritis, schizophrenia, and skin disorders(psoriasis and vitiligo).

     Beta-carotene is used to treat malnourished women by reducing the chance of death and night blindness during pregnancy. The treatment is also aimed toward stopping diarrhea and fever after giving birth.

     Some people who sunburn easily, including those with an inherited disease called erthyropoietic protoporphyria(EPP), use beta-carotene to reduce the risk of sunburn.

     There are many authorities – including the American Heart Association, the American Cancer Society, the World Cancer Research Institute in association with the American Institute for Cancer Research, and the World Health Organization’s International Agency for Research on Cancer – that recommend getting beta-carotene and other antioxidants from food instead of supplements. Eating 5 servings of fruits and vegetables daily provides 6-8 mg of beta-carotene.

     Pumpkin can be prepared in a wide array of scrumptious ways. For example: Protein Pumpkin Pie with Whey Protein Recipe (https://www.gnc.com/health-articles-tips/recipes/protein-pumpkin-pie.html):

2 (9-inch) deep-dish, unbaked pie crusts

5 eggs

2 ½ cups canned pumpkin

6 scoops- GNC performance Whey

1 2/3 cups sugar

1 teaspoon salt

2 teaspoons cinnamon

½ teaspoon ground cloves

2 cans fat-free evaporated milk

     Light whipped cream (optional)

     The pie should be placed on bake, and allowed to cool. Serve it with a dollop of whipped cream.

     Pumpkin is a healthy source of vitamins and nutrients.  It is packed with Beta-carotene.

Tuesday, April 17, 2018

Diphenylamine, apple pesticide

     Go to your nearest edible supplier. Pick up an apple.  What is the powder substance on the sides?  It is a pesticide, which slows down produce mold.  A popular pesticide is diphenylamine.

     Diphenylamine (DPA)-

(Information origination-
Reregistration Eligibility Decision (RED) document fact sheet case 2210, United States Prevention, Pesticides EPA-738-F-97-010 Environmental Protection And Toxic Substances April 1998 Agency (7508W))

     Diphenylamine (DPA) is a plant growth regulator used post-harvest to control storage scald on apples. It is mainly used for its antioxidant properties. As a pesticide, DPA is used for destroying insects or other organisms harmful to cultivated plants.  DPA has been classified as an indoor food use.

     Storage scald- term loosely applied to a group of skin disorders of apples and pears. It involves brown or gray discoloration of irregularly shaped areas on the surface of the fruit during or following storage (http://postharvest.tfrec.wsu.edu/pages/N6I2C)

Chemical formula- C12H11N

Molar Mass- 169.23 g/mol

Appearance- White, tan, amber, or brown crystals

Odor- pleasant, floral

Density- 1.2 g/cm3

Melting point- 53 °C (127 °F; 326 K)

Boiling point- 302 °C (576 °F; 575 K)

Solubility in water- 0.03%

Vapor pressure- 1 mmHg (108°C)

Acidity (pka)- 0.79

Magnetic susceptibility- -109.7·10−6 cm3/mol

     Formulations include an emulsifiable concentrate, a wettable powder, a soluble concentrate/liquid and a ready-to-use liquid.   DPA is applied by dipping, drenching or spraying.  It was pesticide registered in 1947.

     DPA has been shown to be slightly toxic by the oral, dermal, and inhalation routes and has been placed in Toxicity Category III (second lowest of four categories) for these effects.  The dietary intake cancer risk for diphenylnitrosamine is 2.8 x 10 mg/kg/day.

     DPA is of low acute toxicity and has been classified as “Not Likely“ as a human carcinogen. An impurity of DPA,
diphenylnitrosamine, is classified as a “probable human carcinogen”, however the cancer risks for dietary intake and worker exposure fall below the Agency’s level of concern. Food crop use consist of post-harvest use on apples. Dietary exposure to DPA residues in foods is within acceptable limits.

     Since this is considered an indoor food end-use chemical, only hydrolysis data are required. Available data indicate that DPA is stable towards hydrolysis at pH’s 5, 7, and 9. DPA has a moderate solubility in water (39.4 ppm), a relatively high octanol/water partition coefficient (K =3,860), and a high vapor pressure (6.39 x 10 torr). The high rate of ow
-4 aqueous photolysis and the susceptibility of the chemical in aerobic environments indicate that if DPA were to reach surface waters, it would be short lived.

     DPA is moderately toxic to fish and aquatic invertebrates. It is practically non-toxic to avian species on an acute and subacute basis.

     Industrial handling of Diphenylamine- 

     The Agency develops any mitigation measures or regulatory controls needed to effectively reduce each pesticide's risks. EPA then reregisters pesticides that meet the safety standard of the FQPA and can be used without posing unreasonable risks to human health or the environment. When a pesticide is eligible for reregistration, EPA explains the basis for its decision in a Reregistration Eligibility Decision (RED) document. These facts are summarized from the RED document for reregistration case 2210, diphenylamine.